Abstract 11644: Differentiating Hypertrophic Cardiomyopathy From Hypertensive Left Ventricular Hypertrophy Using Quantitative Layer-specific Speckle-tracking Echocardiography

Background: The distinction of mild to moderate hypertrophic cardiomyopathy (HCM) from hypertensive left ventricular hypertrophy (HLVH) may be difficult. The aim of this study was to determine the value of a novel multi-layer transthoracic echocardiography in differential diagnosis between HCM and HLVH. Methods: Sixty eight patients with HCM and preserved LV ejection fraction (82% male, 50±14 years; LVEF 64±8%); age and sex matched with 68 HLVH (56 male; 50±13 years, LVEF 64±8%) and 68 controls (56 male,50±13 years; LVEF 65±6%) underwent STE (GE Vivid-E9). Quantitative layer-specific longitudinal (LS), circumferential (CS) endocardium, mid-myocardium, and epicardium strain as well as radial strain (RS) assessed by 2-dimensional strain echocardiography. Ratios of endo- to epicardium (end/epi) strain were calculated. Results: The absolute value of LS on all layers of hypertrophic segments (Fig. showing LS was normal only in normal thickness of posterior and apical wall) were significantly less but the ratio...