Abstract 15051: Selective Suppression of Aldosterone Production in Non-Human Primates by SE-6440, a Potent and Highly-Selective Inhibitor of Aldosterone Synthase (CYP11B2)

J. David Becherer,Edward P. Garvey,William J. Hoekstra,Robert J. Schotzinger,Steven M. Sparks

Abstract 15051: Selective Suppression of Aldosterone Production in Non-Human Primates by SE-6440, a Potent and Highly-Selective Inhibitor of Aldosterone Synthase (CYP11B2)

2018

J. David Becherer
Edward P. Garvey
William J. Hoekstra
Robert J. Schotzinger
Steven M. Sparks

Introduction: Primary aldosteronism (PA) is a major public health concern given its prevalence and associated cardiovascular and renal pathology. Compared to patients with essential hypertension, p...

Keywords:

Aldosterone
Primary aldosteronism
Aldosterone synthase
Diabetes mellitus
Essential hypertension
Internal medicine
Renal pathology
Endocrinology
Cardiology
Medicine
drug administration
Pharmacology
highly selective

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