Additional file 2: Figure S1. of Skeletal muscle interleukin 15 promotes CD8+ T-cell function and autoimmune myositis

IL-1α/β or LPS induced moderate expression of IL-15/IL-15Rα protein complex in C2C12 myotubes. (A–C) C2C12 myotubes were treated with IFN-α (0 or 10 ng/ml), IL-1α/β (0 or 10 ng/ml), or LPS (0, 0.1, or 1 μg/ml) and examined for the expression of Il15 and Il15ra mRNA at indicated time points. Data represent mean ± SEM of triplicates. (D–F) The level of IL-15/IL-15Rα complex protein in cell lysate and culture medium after 24-h treatment with IL-1α/β, LPS, or IL-1α were measured by ELISA. Data were pooled from two and three independent experiments. Data are mean ± SEM. *p