SUSPICIOUS REGION DETECTION AND IDENTIFICATION BASED ON INTRA-/INTER-FRAME ANALYSES AND FUZZY CLASSIFIER FOR BREAST MAGNETIC RESONANCE IMAGING

Breast cancer is one of the leading causes of death from cancer in Taiwan. In this paper, we propose a feature-based scheme composed of preprocessing, feature extraction and a fuzzy classifier for suspicious region detection and identification. In the preprocessing stage, we first extract regions of interest and then coarsely determine suspicious regions via candidate screening. Some features are extracted based on intra-slice, texture and inter-slice analysis techniques for suspicious region identification. Intra-slice analysis evaluates the intensity and size of suspicious regions. To find a precise region, we propose a region growing algorithm based on ellipse-based approximation. In texture analysis, some texture cues are extracted from spatial and wavelet domains and integrated as a combined texture feature by using a neural network. Inter-slice analysis is based on the continuity characteristic and consistency of a suspicious region's size; the objective is to verify the static behavior of suspicious regions. Several magnetic resonance imaging (MRI) cases are utilized to evaluate the performance of the proposed scheme. Experimental results demonstrate that our scheme can not only extract regions of interest but also identify tumors well from magnetic resonance images.