Enantioselective synthesis of aminobenzazepinones
2007
Abstract Enantioselective synthesis of constrained trans -aminobenzazepinone utilizing palladium-mediated Jeffery–Heck reaction and rhodium(II) catalyzed asymmetric hydrogenation as key steps are described. Diverse functional groups such as alkyl, aryl, basic or amino acid moieties were introduced with minimal racemization.
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