The prediction of treatment outcomes in non-seminomatous extragonadal germ cell tumors (NSEGCT) by using different criteria of « poor » and « good » risk

Multivariate analysis allowed to identify prognostic factors on the treatment outcome and led to perform the current « good risk » and « poor risk » criteria for patients with germ cell tumors (GCT). In spite of common histology, an inferior CR rate in the treatment of NSEGCT patients, in comparison with those reached in testicular cancer have been reported by the most of authors and led to include them in « poor risk » group [1]. Thus all patients with extragonadal primary are automatically include in the « poor risk » definition of the Memorial Sloan Kettering Cancer Center (MSKCC)[2] and the National Cancer Institute criteria [3]. In this study we applied the objective criteria of « good » and « poor » risk performed for testicular tumors to assign NSEGCT patients in risk groups and to predict their treatment outcome.