Utilization of FIXED combination (FC) in the treatment of asthma patients in real life condition in the Czech Republic (UFO)

Moderate and severe asthma is treated by FC of BUD/FOR, SAL/FP and BDP/FOR in the Czech Republic (CR). We do not have any data about real life utilization of FC in asthma treatment in the CR. Primary obj.: Utilization of FC in the treatment of asthma pts. per year 2010. Secondary obj.: To describe asthma treatment in the CR in pts. who were prescribed a FC therapy. Our study looking into the pts. records kept by specialist - allergists (132) and pulmologists (144). Every participating investigator recruited 10 pts. for the study. Asthmatic outpatients older than 6 years (n = 2786) who come to a regular visit were treated with one of three FC for at least 18 months. There were 1,8% pts. with intermittent asthma, 18,8% pts. with mild persistent, 67,6% pts. with moderate persistent, 12,2% pts. with severe persistent including 3,4% pts. with asthma difficult to treat. 60.8% pts. were treated with BUD/FOR (55.9% pts. in convectional regime, 44.1% pts. in the SMART regime), 37.3% pts. were treated with SAL/FP, 1.9% pts. were treated with BDP/FOR). Median of number of pack prescribed per year to pts. with asthma for BUD/FOR in convectional regime was 7 and in SMART regime was 7, for SAL/FP 12, for BDP/FOR 6. Total compliance of using FC was 53%, compliance of using FC in convectional regimes was 48.5%, compliance of using BUD/FOR in the SMART regime was 68%. The utilization of BUD/FOR in SMART regime in the treatment of asthma pts. per year was the same as the utilization of BUD/FOR in convectional regime. Therapy of BUD/FOR in SMART regime increased compliance in comparison with convectional regimes of the other FC.