Research Paper Convenient Synthesis of Some New Diversely Functionalized Coumarinyl Chalcone Derivatives under Microwaves

2013 
Herein we have reported some new coumarinyl chalcones synthesized by conventional method as well as microwave assisted method of synthesis. The reaction of 3-acetyl 4-hydroxy coumarin 2a-c with substituted 1, 3-diphenyl-1H-pyrazole-4-carbaldehyde 6a-h in the presence of piperidine as catalyst and chloroform as a solvent, yielded a series of chalcones 7a-x. The structures of all synthesized compounds are well characterized by Mass, FT-IR, 1 H NMR, 13 C NMR and elemental analysis. After obtaining experimental data regarding the yield and the time taken for the synthesis by both the methods, convenient and microwave assisted method, it was proved that the microwave assisted method is convenient for synthesis of this type of coumarinyl chalcones 7a-x.
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