Circulating plasmablasts/plasma cells: a potential biomarker for IgG4-related disease.
2017
Background
Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a multisystem fibroinflammatory disease. We previously reported that a circulating cell population expressing CD19+CD24−CD38hi was increased in patients with IgG4-RD. In this study, we aimed to document that this cell population represented circulating plasmablasts/plasma cells, to identify the detailed phenotype and gene expression profile of these IgG4-secreting plasmablasts/plasma cells, and to determine whether this B-cell lineage subset could be a biomarker in IgG4-related disease (IgG4-RD).
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
40
References
79
Citations
NaN
KQI