One-pot synthesis of 6H-benzo[b]benzo[4,5]imidazo[1,2-d][1,4]oxazines via a copper-catalyzed process

A convenient and efficient copper-catalyzed one-pot process for the construction of 6H-benzo[b]benzo[4,5]imidazo[1,2-d][1,4]oxazines through reactions of 2-halophenols with 2-(chloromethyl)-1H-benzo[d]imidazoles under mild conditions is described. The reactions afforded a variety of products in good to excellent yields.