Clinical and urodynamic impact of detrusor overactivity in women with overactive bladder

Abstract Objective To evaluate the clinical and urodynamic differences associated with the presence or absence of detrusor overactivity (DO) in women with overactive bladder (OAB) referred to Functional Urology and Urodynamic Units in Spain. Material and methods Observational, cross-sectional, multicenter and prospective study conducted in Spain in women with clinical diagnosis of OAB, who had been referred to urodynamic study (UDS) of which centralized reading was performed. Patients completed the 3-day bladder diary (DM3d) with the PPIUS scale (Patient Perception of Intensity of Urgency Scale), the B-SAQ (Bladder control Self-Assessment Questionnaire) and the OABq-SF (Overactive Bladder Questionnaire Short Form). The questionnaires and UDS variables of women with OAB, with or without DO, were compared using the Mann-Whitney test (continuous variables) and the chi-square test ( χ 2 ) (categorical variables). Results A total of 247 women with OAB were evaluated, and 103 of them had DO. According to the presence or absence of DO, significant differences were observed in the number of episodes of urge urinary incontinence (UUI), urinary frequency, nocturia, mean micturition volume and number of pads ( p p p  = 0.011). Conclusions The presence of DO in women with OAB is related to a more severe alteration of the bladder storage phase.