Eficácia no Tratamento da Depressão: Um Novo Para- digma ao Encontro das Expectativas dos Doentes a) Efficacy in the Treatment of Depression: A New Paradigm to Meet the Patient's Expectations

Background: There is a need to improve the efficacy evaluation methods of the an tidepressants in order to allow the inclusion of symptoms which express more the improvement of the patient expectations. In the present article we present a discussion about the efficacy evaluation of agomelatine, particularly regarding posi