Acute elevation of intra-abdominal pressure contributes to extravascular shift of fluid and proteins in an experimental porcine model
2014
Background
Intra-abdominal hypertension and abdominal compartment syndrome contribute significantly to increased morbidity and mortality in critically ill patients. This study describes pathophysiologic effects of the acutely elevated intra-abdominal pressure on microvascular fluid exchange and microcirculation. The resulting changes could contribute to development of organ dysfunction or failure.
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