The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8 + T cells to respond to foreign antigens
2015
Thymic selection produces a diverse T cell repertoire. Jameson and colleagues demonstrate intrinsic differences in the ability of naive CD8+ T cells to respond to foreign antigen, such that cells with higher self-reactivity dominate the immune response.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
57
References
137
Citations
NaN
KQI