Effect of Vitamin D on Endothelial Function and Blood Pressure

Chronic kidney disease (CKD) is associated with an increased rate of cardiovascular events [1], which is not fully explained by traditional risk factors and is increasingly associated with non-traditional risk factors [2]. Vitamin D deficiency is a non-traditional risk factor for cardiovascular events which becomes more relevant with declining renal function. At the same time, the deficiency of active vitamin D plays a major role in the mineral-bone disease of patients with CKD. The role of vitamin D deficiency in causing cardiovascular complications in the general population has attracted huge attention from researchers in recent years [3]. However, patients with kidney failure deserve further attention due to the role of kidneys in activating vitamin D.