Dose-dependent pharmacokinetics of sulpirideand sulpiride-induced prolactin secretionin man

Sulpiride (SU), a widelyused benzamide neuroleptic, is known to promote rapid prolactin release. Sulpiride plasmalevel and the prolactin response to the most commonly used dose, i.e., 50 and 200 mg sulpiride (ad-ministered orally), were studied inten male volunteers.