Synthesis of an organic-inorganic hybrid absorbent for in-tube solid phase microextraction of bisphenol A.

This research is an application of fiber-in-tube solid phase microextraction followed by HPLC-UV for extraction and determination of trace amounts of bisphenol A. Nano magnetic Fe3 O4 was formed on the surface of polypropylene porous hollow fibers to increase the surface area and then it was coated with polystyrene. The introduction of polystyrene improves the surface hydrophobicity and is an appropriate extractive phase because it is highly stable in aquatic media. The extraction was carried out in a short capillary packed longitudinally with the fine fibers as the extraction medium. Extraction conditions, including extraction and desorption flow rates, extraction time, pH, and ionic strength of the sample solution, were investigated and optimized. Under optimal conditions, the limit of detection was 0.01 μg L-1 . This method showed good linearity for bisphenol A in the range of 0.033-1000 μg L-1 , with the coefficient of determination of 0.9984. The inter- and intra-day precisions (RSD%, n = 3) were 7.9% and 6.3%, respectively. Finally, the method was applied to analysis of the analyte in thermal papers, disposable plastic cups, and soft drink bottles. This article is protected by copyright. All rights reserved.