A phase II trial of biweekly gemcitabine and paclitaxel with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN): SWOG study S0329

Background A phase I study and an institutional pilot study in patients with metastatic/recurrent squamous cell carcinoma of the head and neck (SCCHN), utilizing biweekly gemcitabine-paclitaxel showed an overall response rate of 53%. This phase II trial was conducted to determine the feasibility, tolerability and efficacy of this combination.