Synthesis of fluorinated pyrimidines by the reaction of perfluoro-2-methylpent-2-ene with amidines

4-Fluoro-6-pentafluoroethyl-5-trifluoromethylpyrimidines have been synthesized by the reaction of perfluoro-2-methylpent-2-ene with aceto- and trifluoroacetoamidines. The high activity of the fluorine atom at position 4 of these compounds in reactions with nucleophilic reagents was found.