Interaction between NUDT15 and ABCC4 variants enhances intolerability of 6-mercaptopurine in Japanese patients with childhood acute lymphoblastic leukemia

Yoichi Tanaka,Hisaya Nakadate,Kensuke Kondoh,Kozue Nakamura,Katsuyoshi Koh,Atsushi Manabe

Interaction between NUDT15 and ABCC4 variants enhances intolerability of 6-mercaptopurine in Japanese patients with childhood acute lymphoblastic leukemia

2017

Yoichi Tanaka
Hisaya Nakadate
Kensuke Kondoh
Kozue Nakamura
Katsuyoshi Koh
Atsushi Manabe

Interaction between NUDT15 and ABCC4 variants enhances intolerability of 6-mercaptopurine in Japanese patients with childhood acute lymphoblastic leukemia

Keywords:

Genetics
Genomics
Functional genomics
Biology
Drug development
Childhood Acute Lymphoblastic Leukemia
Mercaptopurine
ABCC4
Bioinformatics
Proteomics
Cumulative incidence
Leukopenia
Proportional hazards model
Candidate gene

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