Fischer indolization of 2-sulfonyloxyphenylhydrazones: A new and practical approach for preparing 7-oxygenated indoles and application to the first synthesis of eudistomidin-A. (Fischer indolization and its related compounds. Part 28)☆☆☆
1998
Abstract An efficient method for synthesis of 7-oxygenated indoles was established by Fischer indolization of the phenylhydrazones ( 10 ) with a sulfonyloxy group at the ortho -position. This method was applied to the first synthesis of the calmodulin antagonist eudistomidin-A ( 2 ).
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