Immunotherapeutic approaches for soft-tissue sarcoma: Augmentation of natural killer cell cytotoxicity by ex-vivo expansion and use of an anti-GD2 antibody.

Veit Buecklein,Tobias Jorg,Desiree Pass,Christina Krupka,Patrick Schlegel,Peter Lang,Hans Hoffmeister,Lars H. Lindner,Wolfgang Hiddemann,Marion Subklewe

Immunotherapeutic approaches for soft-tissue sarcoma: Augmentation of natural killer cell cytotoxicity by ex-vivo expansion and use of an anti-GD2 antibody.

2016

Veit Buecklein
Tobias Jorg
Desiree Pass
Christina Krupka
Patrick Schlegel
Peter Lang
Hans Hoffmeister
Lars H. Lindner
Wolfgang Hiddemann
Marion Subklewe

e14528Background: Patients with advanced soft-tissue sarcoma (STS) have a poor prognosis with high relapse rates. Immunotherapeutic strategies aim to eradicate quiescent malignant cells as origin o...

Keywords:

Natural killer cell
Anti-GD2 Antibody
Pathology
Cancer research
Cytotoxicity
Soft tissue sarcoma
Ex vivo
Medicine
Sarcoma
malignant cells
ex vivo expansion
poor prognosis

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