Atherosclerosis and ω-3 fatty acids in the populations of a fishing village and a farming village in Japan

Abstract The effect of different dietary habits on atherosclerosis was investigated by examining the content of ordinary diets and relevant risk factors through a mass health survey on two village populations in Japan. In total, 261 inhabitants in the fishing village and 209 in the farming village were examined for body build, blood pressure, and blood chemistry. Information on smoking habits and food consumption was obtained using a semi-quantitative item-frequency questionnaire. Pulse wave velocity of the aorta, intima-media thickness of the carotid artery, and atherosclerotic plaques as obtained by ultrasonography were used as measures of atherosclerosis. All measures of atherosclerosis are lower in the fishing village than in the farming village in both men and women. There is a striking 5–8-fold difference in the number of atherosclerotic plaques ( P ω -3 fatty acids over the combined populations reveals a negative association with the number of plaques in the common carotid while the ω -6 fatty acids shows a weak positive association with plaques.