Diabetic Peripheral Neuropathy Is Associated with Elevated Systolic Blood Pressure in non-hypertensive patients with type 2 diabetes and affect hypertensive management

Abstract Aims Investigate association between diabetic peripheral neuropathy (DPN)and above normal blood pressure in non-hypertensive patients with type 2 diabetes mellitus(T2DM). Compare the achievement of clinical target for DPN and non-DPN withT2DM . Methods A retrospective survey was administered to 3810 patients with type 2 diabetes. Cases were grouped according to the Toronto Clinical Scoring System (TCSS): Non-DPN, Mild DPN, Moderate DPN and Severe DPN. 1835 patients (HT/non-HT = 1247/588) additionally received nerve conduction velocity test (NCV), after which a quadruple grouping of P ≤ 25% - P> 75% was calculated. Results Irrespective of hypertension, systolic blood pressure (SBP)and A1c levels in the DPN group were higher than non-DPN group levels (P 75% groups decreased by 62.2%, 68.2% and 78.0%, respectively. In non-hypertensive patients, detection of optimal SBP was lower in the DPN group than in the non-DPN group (P Conclusions DPN is associated with hypertension management difficulty in type 2 diabetes. Even in non-hypertensive patients with diabetes, DPN is associated with elevated systolic blood hypertension. Elevated SBP in non-hypertensive type 2 diabetes may be also worthy of attention.