Validation of a diphtheria toxoid multiplex bead assay for serosurveys.
2021
Abstract We validated a multiplex bead assay for diphtheria toxoid IgG antibodies against the Vero cell toxin neutralization test using 1,300 specimens (correlation=0.88). At the ≥0.01 IU/ml cutoff for minimal seroprotection, sensitivity was 95% and specificity was 83%. Agreement for three categories (
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