Invitro Evaluation of Antimicrobial Efficacy of Indigenously Prepared Neem and Aloe vera leaf extracts at Various Concentrations & Comparison with 3% Sodium hypochlorite against E. faecalis and C. albicans by Agar Diffusion Method

Aim : The aim of study was to determine the antimicrobial efficacy of alcoholic Neem and aloevera leaf extracts against E.faecalis and C.albicans. Materials & methods : In the present study indigenously prepared Neem and Aloevera leaf extracts were serial diluted to determine the minimum inhibitory concentration (MIC) at which the E.faecalis and C.albicans were sensitive and compared it with 3% Naocl by agar well diffusion method. Results :. The minimum inhibitory concentration (MIC) of the alcoholic neem extract to E. faecalis & C. albicans were determined as 0.94% &1.88% & for aloevera extracts it was 1.88% & 3.75% respectively .The efficacy of these extracts were significantly greater than 3%Naocl when compared by one way Anova statically analysis. Conclusion: The antimicrobial efficacy of extracts in comparison with 3% Naocl was well demonstrated from the present invitro observation of agar well diffusion method and it may be advantageous if we use these extracts as irrigating solutions in endodontics. However it requires further preclinical and clinical evaluation..