A case of X linked agammaglobulinaemia complicated with systemic amyloidosis

Editor,—We recently cared for a 27 year old man who died of multiple organ failure caused by systemic amyloidosis. Immunoperoxidase staining of a rectal biopsy specimen showed AA-type amyloid fibrils. He had been diagnosed at the age of 14 months as having X linked agammaglobulinaemia (XLA), presenting with a history of recurrent pneumonia and skin …