Distinct targets for blue light photoinactivation (Conference Presentation)

Our aim was to evaluate membrane integrity and the occurrence of possible DNA damage caused by blue light inactivation. We used in our study three bacterial pathogens with distinct biochemical and morphological characteristics: Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Through electrophoresis and fluorescence spectroscopy analysis we observed distinct molecular damage between the evaluated microorganisms. Thus, our results suggest distinct mechanisms of inactivation by light blue among different pathogen species. Individual biochemical characteristics of each microorganism may be responsible for the occurrence of distinct structural damage