EWS/ETS Regulates the Expression of the Dickkopf Family in Ewing Family Tumor Cells

Background The Dickkopf (DKK) family comprises a set of proteins that function as regulators of Wnt/β–catenin signaling and has a crucial role in development. Recent studies have revealed the involvement of this family in tumorigenesis, however their role in tumorigenesis is still remained unclear.