STUDY REGARDING THE INFLUENCE OF VITIS VINIFERA FRUIT (MUSCAT OF HAMBURG SPECIES) ON SOME BIOCHEMICAL PARAMETERS

The complex chemical composition of Vitis vinifera fruits (as well as its juice) because of the presence of resveratrol, is one of the strongest antioxidants known [1]. Tests performed in this study include the way in which certain biochemical parameters, such as glycemia, serum lipids, cholesterolemia, LDL-cholesterol (low density lipoproteins-cholesterol), HDL-cholesterol (high density lipoproteins-cholesterol), nonnitrogenous substances and activity of serum transaminases, were influenced by the consumption of Vitis vinifera fruit extract. The determinations were performed on uniform groups of Wistar rats, selected in advance that were treated orally with 10 % aqueous extracts of seeds, fruit skin and pulp extract of Vitis vinifera Muscat of Hamburg species. The results revealed that there was a slight decrease in the level of blood glucose, which was 9.15% for the group treated with the skin extract. The decrease in cholesterolemia was 13.98% for the animals treated with the fruit skin extract and 12.8% for the animals that received seeds extract, while that for LDL-cholesterol and triglycerides after the administration of extract from grape peel was 11.99% and 12.44% respectively. There was a pronounced decrease in the non-nitrogenous substances, mostly uric acid with 15.09% for the grup treated with fruit skin extract. Serum creatinine and the activity of serum transaminases did not show significant changes.