[The seasonal dynamics of the indices of the oxidative-reductive processes in the erythrocytes of healthy subjects of different ages].

A study is reported of the dynamics of the activity of enzymes markers of different metabolic ways--glycolysis, pentosophosphate cycle, gluconeogenesis--in erythrocytes of 157 practically healthy subjects in two age groups: from 20 to 35 years and from 35 to 60 years. It was shown that seasonal biorhythms of the above values that were definite in the young changed with age. These findings suggest the necessity of a chronobiological approach to research and clinico-laboratory investigations.