Optical biosensor system for the quick and reliable detection of virus infections: VIROSENS
2014
Viral infections are of special threat because they can induce severe courses of disease but only few medical treatments
are available. Because of socio-economic and climate changes, increased worldwide mobility and population growth, the
risk of newly occurring and quickly spreading viral pathogens has increased. A diagnosis of these diseases at an early
stage is essential for a quick risk assessment and a proper health management as well as patient’s treatment in an optimal
way. Currently, the diagnosis of such diseases is based on time consuming and costly detection methods that can only be
performed by specially trained personnel in laboratories at specific security levels.
Aim of the project VIROSENS is the development of a biosensor platform that can specifically detect virus particles as
well as virus-specific antibodies out of biological matrices like blood, serum, plasma and other body fluids. For this
purpose, a disposable cartridge for such antibody- and virus-arrays is designed and developed within the project. The
optical detection of viruses is performed with a portable device that will be benchmarked and evaluated concerning
currently used standard detection methods in terms of its analytical performance.
Within this project, a novel combination of serological tests and direct detection of virus particles will be developed,
which will provide faster and more reliable results than presently available and used test systems.
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