Convenient Synthesis of 11‐Substituted 11H‐Indolo[3,2‐c]quinolines by Sequential Chemoselective Suzuki Reaction/Double C–N Coupling
2017
A pathway to access 11-substitued 11H-indolo[3,2-c]quinolines is described. The protocol features a chemoselective Suzuki reaction of ortho-dihaloquinolines with ortho bromophenylboronic acid, followed by a double C-N coupling with primary amines. The molecular structure of a representative product is exemplified, demonstrating well defined pi-stacking interactions in the molecular network.
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