Metabolic brain circulation of serotonine and dopamine in patients with brain organic psychosyndrome

2000 
Brain organic psychosyndrome (BOPS) in psychiatry and neuroscience represents an entity based on cognition dysfunction, arisen as a result of multicausal brain damage dispersion. Contemporary imaging diagnostic mostly proves the alteration of biogenic amins (serotonine and dopamine) and their metabolotes in patients with BOPS. Two groups of patients are treated and compared to the control group of patients with BOPS diagnosis and causal brain damage by infarction lesions (group A) and long-time alcohol abuse patients (group B). In liquour of internal brain microenvironment and neurones levels and oscillations of concentration of serotonine, dopamine and their metabolites often correlates with cognitive damages which are defined by psychometric methods. This research also goes to prove the connections of murometabolic disbalance in liquor with dysfunction of cognition and in patients with ischemic brain damage, as well as neurone quantum loss in MOPS. Resides, our research aims at proving alternation of biogenic amines (serotonine) in group with ishemic brain damage and in group with alcohol related brain damage.
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