Predictive factors for weight loss following pancreatic resection

BACKGROUND: In pancreatic cancer, postoperative weight loss is associated with higher mortality. This study assessed preoperative factors associated with postoperative weight loss so that at-risk patients can be identified for intervention. METHOD: A retrospective review of patients who underwent pancreatic surgery was completed. Demographics and routine blood work were analyzed to determine association with postoperative weight loss. RESULTS: Of 74 patients, 85% lost weight after surgery. Weight loss was associated with time since surgery, preoperative weight, and preoperative albumin, making patients who appear best nourished the most at-risk. CONCLUSIONS: Weight loss was prevalent. in contrast to conventional assessment, patients who weighed more and had higher serum albumin lost the most weight. An interprofessional team may help to address this disparity.