Cardioprotective Effect of Beta-3 Adrenergic Receptor Agonism: Role of Neuronal Nitric Oxide Synthase: Beta3-AR prevents cardiac dysfunction through nNOS

Xiaolin Niu,Vabren L. Watts,Oscar H. Cingolani,Vidhya Sivakumaran,Jordan S. Leyton-Mange,Carla L. Ellis,Karen L. Miller,Konrad Vandegaer,Djahida Bedja,Kathleen L. Gabrielson,Nazareno Paolocci,David A. Kass,Lili A. Barouch

Cardioprotective Effect of Beta-3 Adrenergic Receptor Agonism: Role of Neuronal Nitric Oxide Synthase: Beta3-AR prevents cardiac dysfunction through nNOS

2012

Xiaolin Niu
Vabren L. Watts
Oscar H. Cingolani
Vidhya Sivakumaran
Jordan S. Leyton-Mange
Carla L. Ellis
Karen L. Miller
Konrad Vandegaer
Djahida Bedja
Kathleen L. Gabrielson
Nazareno Paolocci
David A. Kass
Lili A. Barouch

Objective The aim of this study is to determine if activation of β3-adrenoceptor (β3-AR) and downstream signaling of NOS isoforms protects the heart from failure and hypertrophy induced by pressure overload.

Keywords:

Neuronal Nitric Oxide Synthase
Gene isoform
Beta-3 adrenergic receptor
Pressure overload
Diabetes mellitus
Upstream and downstream (transduction)
Endocrinology
Muscle hypertrophy
Medicine
Internal medicine
nos isoforms
cardiac dysfunction

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations