EFFECT OF MITOMYCIN C APPLICATION ON HEAD AND NECK KELOIDS

AIM: To find out the effect of mitomycin application along with surgical excision on keloid recurrence rates. METHODS: A prospective study of 20 study subjects treated for head and neck keloids carried out at JJM Medical College, Davangere. After removing core of Keloid by sharp dissection, Mitomycin C (0.8mg/cc) soaked cotton pledgets were applied over the wound for 5 minutes. Later wound was irrigated with normal saline. Tensionless wound closure was carried out RESULTS: Weekly post-operative follow-ups were done. Patients did not report any adverse skin reactions or side effects that could be attributed to the mitomycin-C. Only 1 out of the 20 subjects had a recurrence of keloid after a 6 months followup. CONCLUSION: Combination of surgical excision with topical mitomycin-C application is highly effective in treating head and neck keloids.