Comment: The elusive search for markers of hematoma expansion

Hematoma expansion occurs in up to 40% of intracerebral hemorrhage (ICH) patients within 6 hours from the onset. Stopping the expansion is one aim of randomized clinical studies,1 and an important clinical imperative. CT angiography (CTA) spot sign is a known marker, found in about 30% of patients. Ultraearly hematoma growth (uHG) (expressed as the ratio between hematoma volume [mL] and time [h] from onset to imaging acquisition) is also a useful marker of hematoma expansion.