Tracing of Cancer Cell-Specific Cytotoxic Drugs by Laser Ablation ICP-MS

Michaela Vašinová Galiová,Roman Hrstka,Kristýna Štůlová,Kristýna Koubková,Jindřich Karban,Jiří Pinkas,Viktor Kanicky

Tracing of Cancer Cell-Specific Cytotoxic Drugs by Laser Ablation ICP-MS

2016

Michaela Vašinová Galiová
Roman Hrstka
Kristýna Štůlová
Kristýna Koubková
Jindřich Karban
Jiří Pinkas
Viktor Kanicky

The aim of this study was to record the distribution of central atoms of selected drugs within the cell and tumor tissue. For this purpose, LA-ICP-MS was employed. Solution analysis ICP-MS was used to study total metal uptake by cells depending on anti-cancer drug structure.

Keywords:

Radiochemistry
Cancer cell
Cell
Laser ablation
Cytotoxic T cell
Inductively coupled plasma mass spectrometry
Study.total
Tracing
Drug structure
Chemistry
Analytical chemistry
solution analysis
Pharmacology

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