Pengaruh Vaksin BCG dalam Meningkatkan Proses Segresi Seluler pada Lesi Prakanker Serviks Uteri Derajat Rendah
2020
Tujuan : Penelitian ini adalah untuk menganalisis peranan pemberian vaksin bacille calmette-guerin (BCG) terhadap proses regresi seluler pada lesi prakanker serviks uteri derajat rendah Metode : Penelitian ini merupakan penelitian eksperimental dengan rancangan pretest (IVA dan Histopatologi) - posttest (IVA dan Test HPV DNA) with control design di Poliklinik Rumah Sakit Dr. Hasan Sadikin Bandung pada bulan Desember 2017-Maret 2018. Hasil : Untuk pemeriksaan IVA bulan ke-0 pada kelompok BCG kategori positif sebanyak 9 (100.0%) sedangkan untuk pemeriksaan IVA bulan ke-3 pada kelompok BCG kategori positif sebanyak 3 (33.3%) dan negatif menjadi sebanyak 6 (66.7%), pemeriksaan tes HPV DNA bulan ke 12 pada kelompok BCG kategori positif HPV DNA High Risk tidak ditemukan ( 0 % ). Hasil uji statistik pada kelompok perlakuan diperoleh nilai p 0.05. Kesimpulan : Terdapat peranan pemberian vaksin BCG terhadap regresi seluler lesi prakanker serviks derajat rendah. The effect of Bacille Calmette-Guerin vaccine on regression of cervical intraepithelial neoplasia-1 Abstract Objective : The aim of this study was to analyze the role of Baccile Calmete Guerin (BCG) vaccines delivery in low grade precancerous cervical lesions. Methods : The design of the study was a pretest and posttest experimental with control, done at Hasan Sadikin Hospital Bandung Outpatient Clinic during December 2017–March 2018. Result : Patients with positive VIA test in the intervention group in month-0 were 9 patients (100.0%), in month-3 were 3 patients (33.33%) and the other 6 patients (66.7%) changed into negative. Patients with positive VIA test in the control group in month-0 were 9 patients (100.0%), in month 3 were 8 patients (88.9%) and the other 1 patients (11.1%) changed into negative. The result of statistical analysis in the intervention group was p 0.05. Conclusion : : there is a role of BCG vaccine in low grade precancerous cervical lesions. Key words : BCG vaccine, VIA test, Low grade cervical precancerous lesions.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI