Rapidly progressive pulmonary fibrosis in COVID-19 pneumonia
2021
Introduction. COVID-19 pneumonia doesn’t have a characteristic course and
prognosis. Many facts still remain hidden, mainly why certain patients
develop complications with serious tissue damage and whether it causes a
permanent organ impairment. If and when will fibrosis develop in COVID-19
pneumonia requires further research, but a link between the amount of tissue
afflicted and the development of fibrosis exists. Case outline. A
previously healthy, non-smoker, woman with minor symptoms on admission had
suddenly developed a serious respiratory insufficiency and whose
radiographic finding on computed tomography scan had shown a serious
progression with the development of fibrosis in a matter of days. The exact
mechanism and correlation of this clinical course remains unknown; however,
it is clear that the pulmonary fibrosis is caused by COVID-19 pneumonia.
Follow-up computed tomography scan, performed 50 days after initial
symptoms, had shown a partial regression of consolidations and
post-inflammatory fibrosis. Conclusion. Pulmonary fibrosis is the most
severe complication of COVID-19 infection on the respiratory system. Who,
when and if will develop any complication is still unclear, as well as if
these changes are reversible? Also, the number of recovered patients who
later develop any of the chronic complications remains to be seen.
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