PD14-04 SPECTRUM OF RADIOLOGICAL FINDINGS OF HEREDITARY LEIOMYOMATOSIS AND RENAL CELL CANCER (HLRCC).

0.5 mg/dL), perioperative CRP kinetics (non-elevated before CN vs. normalized after CN vs. non-normalized after CN), lactate dehydrogenase, corrected calcium, tumor histology, pT stage, and pN stage. Skeletal muscle index (SMI) was calculated by skeletal muscle areas at the L3 vertebra level normalized for height on diagnostic CT taken preoperatively ( 1 month before CN) and postoperatively (5-6 months after CN). Patients were considered to show SM recovery when postoperative SMI surpassed preoperative SMI. We examined variables associated with overall survival (OS) using the Cox proportional hazards model. RESULTS: Of the 30 patients, 16 (53%) showed SM recovery after CN. SM recovery was not associated with other variables including preoperative CRP. During the median follow-up of 61 months for survivors, 14 patients died (5-yr OS rate 46%). On multivariate analysis, postoperative SM recovery was a significant and independent predictor for OS (HR 0.04, p < 0.001) along with elevated preoperative CRP (HR 13.6, p < 0.001). The 5-yr OS rates for patients with and without SM recovery were 76% and 10%, respectively (p < 0.001). CONCLUSIONS: Postoperative SM recovery is associated with favorable prognosis in mRCC patients who underwent CN.