植物抗病基因同源序列（RGA）研究进展

Using either map-based cloning or transposon tagging, up to 48 resistance genes (R genes) have been isolated from different plant species. Molecular characterization of these genes uncovered common sequence motifs, even though they confer resistance to a wide spectrum of pathogens. These genes encode proteins that can be grouped into several superfamilies, NBS-LRR, eLRR, LRR-STK and so on, based on the conserved protein domains. PCR was performed with the degenerate primers based on these conserved domains, then the resistance gene analogs (RGA) was obtained. This review tries to analyze the relationships between the RGA and R genes, and summarize the important functions of RGA in mapping R genes and the evolution of R genes. It also believes that RGA can be useful as candidate genes to detect and eventually isolate numerous R genes in agronomically valuable plants.