Pharmacokinetics of Troglitazone in Patients with Renal Insufficiency

Philip W. Knowlton,Cho-Ming Loi,Artemios B. Vassos,Robert A. Blum,Joanne I. Brodfuehrer,Edward J. Randinitis,Allen J. Sedman,Jeffrey R. Koup

Pharmacokinetics of Troglitazone in Patients with Renal Insufficiency

1999

Philip W. Knowlton
Cho-Ming Loi
Artemios B. Vassos
Robert A. Blum
Joanne I. Brodfuehrer
Edward J. Randinitis
Allen J. Sedman
Jeffrey R. Koup

Objective: The pharmacokinetic profiles of troglitazone and two metabolites were evaluated following a single 400mg oral dose of troglitazone in 20 patients with various degrees of renal function.

Keywords:

Troglitazone
Renal function
Diabetes mellitus
Medicine
Pharmacokinetics
Internal medicine
Endocrinology
in patient
oral dose
Urology
normal renal function
Anesthesia

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