Typhoid and paratyphoid fever in 192 hospitalized children in Thailand.

• From 1977 to 1984, Salmonella typhi was isolated from 85% and Salmonella paratyphi A was Isolated from 15% of 192 Thai children with enteric fever at children's Hospital, Bangkok. Children with enteric fever presented with sudden onset of fever and gastrointestinal symptoms. Diarrhea occurred in 62% of children with paratyphoid fever and 36% of children with typhoid fever. Rose spots were seen in 15% of patients with typhoid and 7% of patients with paratyphoid fever. There were no deaths. Bronchitis and pneumonia occurring In 11% of patients were the most common complications. Acute hemolysis occurred in 3% of the patients with typhoid fever who had thalassemia or glucose-6-phosphate dehydrogenase deficiency. Chloram-phenicol-resistant S typhi , which accounted for 70% of the isolates in 1977, has since 1982 accounted for less than 2% of isolates. ( AJDC 1987;141:862-865)