Tumor-Derived Chemokine CCL5 Enhances TGF-β–Mediated Killing of CD8+ T Cells in Colon Cancer by T-Regulatory Cells
2012
This intriguing study tightens the emerging connections in cancer between inflammation, immune escape, and metastasis by showing how a chemokine implicated in inflammation and metastasis also drives immune escape by recruiting Treg cells that promote progression into tumors.
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