New dithiolopyrrolone antibiotics from Saccharothrix sp. SA 233: I. Taxonomy, fermentation, isolation and biological activities
2002
Three new natural antibacterial and antifungal dithiolopyrrolone antibiotics were isolated along with the known iso-butyropyrrothine and thiolutine from the fermentation broth of an actinomycete strain which was isolated from a saharian palm grove soil collected at Adrar, south Algeria. The strain was identified as Saccharothrix sp. The three new antibiotics exhibited broad antimicrobial activity against Gram-positive bacteria, yeasts and fungi in vitro.
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