In vitro antitumor activity of rebeccamycin analog (NSC 655649) against pediatric solid tumors

Purpose: This study determined the in vitro antitumor activity of a rebeccamycin analog (NSC# 655649) using tetrazolium/formazan (MTT) and clonogenic assays against established pediatric cell lines and solid tumor specimens obtained from children.Materials and Methods: Tumor cells from 14 establishe