Two new compounds with antimicrobial activities from the seeds of Voacanga africana

Abstract Two new compounds, ( R )-4-(2-methylpentyl)-4 H -dithieno[2,3- b :3′,2′- e ]pyran ( 1 ) and 4-(2-ethylbutyl)-4 H -dithieno[2,3 -b :3′,2′ -e ]pyran ( 2 ) were extracted from the seeds of Voacanga africana . The molecular structures of these compounds were measured with the help of broad spectroscopic ( 1D and 2D-NMR , IR , ESI-TOF-MS , HR-MS ) analyses. The primary pharmacological operations of these compounds were brought to evaluation by applying the antibacterial extrasomatic test. The results revealed that compound 1 and 2 were in an effective position to stop the growth of Escherichia coli , Streptococcus and Salmonella typhi . On the other hand, the inhibitory impacts on Staphylococcus aureus as well as Pseudomonas aeruginosa were not apparent.