Incidence Of Acute Kidney Injury Due To Contrast Usage In Patients Admitted To Mofid Children Hospital (2019-2020)

Background and aims: Contrast-induced renal impairment endangers the patients' health and imposes a financial burden on families and the health care system. Therefore, this study was conducted to examine the rate of nephropathy in patients admitted to Mofid Children's Hospitalin 2018 and 2019.Methods:In this cross-sectional study serum creatinine was measured at baseline and 48-72 hours after CT-scan an increase of more than 25% in serum creatinine was considered CIN. Paired sample t-test was used to assess the change in theCr. The research data were analyzed using SPSS-25 software and the significance level in all tests was set at P = 0.001.Results:In this study, 180children underwent contrast-enhanced CT-scan with a mean age of 5.72 years, of whom 81 (45%) were girls and 99 (55%) were boys. The mean baseline creatinine was 0.633 ± 0.137 mg / dl, which increased significantly to 0.675± 0.164 mg / dl 48-72 hours after the first measurement. The chance of developing ARF in ciprofloxacin users was 4.86 times higher than patients who did not use this drug.Conclusion: In children underwent CT scan, the incidence of ARF is 17.2%. Ciprofloxacin increases the risk of acute kidney problems by 4.8 times.